Ganoderma lucidum, or reishi, is known to have adaptogenic properties. Reishi helps support the function of the adrenal glands. These secrete cortisol, which is a hormone that helps the body respond to stress   Ganoderma has multiple hepatoprotective effects on various liver injury, including hepatocellular carcinoma, nonalcoholic liver disease, alcoholic liver disease, hepatitis B, inflammation, fibrosis, and toxicant-induced liver injury, has shown good clinical outcomes in the treatment of insomnia, restlessness, and palpitation.  Reishi mushrooms had the strongest action in inhibiting testosterone (3). That study found that reishi mushrooms significantly reduced levels of 5-alpha reductase, preventing conversion of testosterone into the more potent DHT.